Amino-the gung sucking hydrochloride easy to store

 Rimonabant (rimonabant in. SR141716) has entered Phase III clinical trials, can effectively reduce weight, and no significant adverse reactions. CB,-R blocker for the treatment of obesity is expected to bring a new dawn. So we can see, rimonabant The synthesis of great significance. Synthesis of 2.2 rimonabant: Rimonabant structured, we can see that rimonabant by several important part of the portfolio Form: acetone, chlorobenzene, 1 - amino the gung throat and 2, 4 twelve chlorobenzene navel. Chloropropiophenone alkali reagents.  The leading principle of the meizitang is to enhance the seepage force of cells.

 The total yield of 15.4. Chemical structure: Proved by the NMR spectra. Two. 2, the synthesis method of the four twelve chlorobenzene Lin. Reaction temperature, feed ratio and restore.The agent of choice. Finally got a good reaction conditions, aniline by amino protection.  The mal-fat cells metabolism can be especially accelerated. Protection, chlorination, hydrolysis, and, and the process of synthesis of 2, 4-dichloro-aniline, the final yield of 55.3. The process route is simple, safe and easy operation, the amount of waste generated in the synthesis process, the use of lye.

Amino-the gung sucking hydrochloride easy to store, short reaction time, reaction     Moderate, high yield, the final yield of 45. Simple post-processing is an easy to operate by Economic use of synthetic methods. 4 this article, try to test instead of the file reagents and silicon reagents mentioned in the literature as base sodium hydride and sodium ethoxide. Agent, and oxalic acid diethyl cool condensation Preparation of 4-chlorophenyl-3-methyl-2, 4 - dione acid ethyl ester. Experimental results show that ethanol sodium as the alkali reagent, 4-chlorophenyl-3-methyl-2 '-dione.  The meizitang is totally made of natural essence of alga.